Flexeril Cyclobenzaprine Hcl: Uses, Dosage, Side Effects, Interactions, Warning

This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include IBM Watson Micromedex (updated 3 Sep 2023), Cerner Multum™ (updated 28 Aug 2023), ASHP (updated 10 Aug 2023) and others. Abuse of muscle relaxants alone is uncommon; often, it involves other substances. Researchers look at emergency room visits and calls to poison control centers to determine the extent of drug abuse for medications. After all, people with an addiction issue tend to take a lot of the target drug, and they often take doses too close together.

• You shouldn’t combine this muscle relaxer with another sleep aid or alcohol.
• Monitoring of plasma drug levels should not guide management of the patient.
• The combination of Flexeril and alcohol can cause serious problems in the central nervous system, the consequences of which may end up being fatal.
• One of the most important bodily processes that these two drugs can end up impacting is respiration.
• The drug is intended to be taken orally, swallowed in tablet form in recommended doses.

In a similar way that Flexeril affects heart rate, it can also compromise respiration. Difficulty in breathing, initially leading to a complete stoppage, can be a possible outcome of this prescription muscle relaxer. The drug is metabolized mainly in the liver by the cytochrome enzymes and excreted in urine by the kidneys. Taking MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. Most MAO inhibitors should also not be taken for two weeks before treatment with this medication.

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This medication is not recommended for use in older adults because they may be at greater risk for side effects while using this drug. Analysis of the data from controlled studies shows that FLEXERIL produces clinical improvement whether or not sedation occurs. Other potential effects of overdosage include any of the symptoms listed under ADVERSE REACTIONS. The plasma concentration of cyclobenzaprine is increased in patients with hepatic impairment (see CLINICAL PHARMACOLOGY, Pharmacokinetics, Hepatic Impairment).

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When taking this drug with an MAOI or within 14 days of stopping an MAOI, it can result in serious side effects such as seizures. It is very possible that Cyclobenzaprine can interact with other medications, vitamins, or even herbs that you may be taking. Drug interactions occur when a substance changes the way a drug works. If these effects are mild, then they are known to go away quickly, within a few hours. If not, they may go away within a few days or a couple of weeks.

Does Cyclobenzaprine Help with Anxiety?

Check with your physician for additional information about side effects. Adding plans allows you to compare formulary status to other drugs in the same class. Tricyclic antidepressants have been reported to produce arrhythmias, sinus tachycardia, prolongation of the conduction time leading to myocardial infarction and stroke. Less frequent dosing should be considered for hepatically impaired or elderly patients (see PRECAUTIONS, Impaired Hepatic Function, and Use in the Elderly).

Our Flexeril (cyclobenzaprine) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. A Flexeril addiction is treatable and it is never too late to reach out for help to begin the recovery process. Different types of addiction treatment are available to fit your specific needs. If you believe you’re addicted to Flexeril, please don’t put off getting help. It’s important to talk with an addiction treatment specialist as soon as you can.

You are encouraged to report negative side effects of prescription drugs to the FDA. Based on the findings, FLEXERIL should be used with caution in subjects with mild hepatic impairment starting with the 5 mg dose and titrating slowly upward. Due to the lack of data in subjects with more severe hepatic insufficiency, the use of FLEXERIL in subjects with moderate to severe impairment is not recommended. Cyclobenzaprine reduced or abolished skeletal muscle hyperactivity in several animal models.

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While the addictiveness of cyclobenzaprine is being debated, anyone exhibiting problematic patterns of substance use can benefit from addiction treatment. This is especially true if someone has been engaging in polydrug what kind of medication is flexeril use with cyclobenzaprine and other substances. How cyclobenzaprine (Flexeril) works is not well understood, but it helps alleviate stiffness, pain, and discomfort due to sprains, strains, or injuries to muscles.

Do not start, stop, or change the dosage of any medicines without your doctor’s approval. Cyclobenzaprine can increase the effects of CNS depressants, such as alcohol, opioids, allergy medications, and sleeping pills. This enables the provider to evaluate for any potential interactions and helps them keep the patient safe.